Domišljijska zgodba po romanu Roalda Dahla govori o majhnem dečku in ljubeči babici, ki se upreta skupini zlobnih čarovnic, ki hočejo vse britanske otroke spremeniti v miši.
A recently orphaned young boy is taken to a seaside hotel in England by his grandmother, who is recuperating after an illness.. Also staying at their hotel is a group of witches who have gathered to prepare a plot to rid England of all children.