Mladi Drew Baylor nekega dne ostane brez službe. Ko je čisto na dnu, ga prizadene še druga tragedija, saj mu nenadoma umre oče. Drew mora sedaj odpotovati v mestece, kjer se je oče rodil in umrl, ter pripraviti vse za pogreb. Ne sluti, da bo to potovanje za vedno spremenilo njegovo življenje. Na poti v Elizabethtown spozna stevardeso Claire, ki mu s sproščenostjo, optimizmom in voljo do življenja vlije novih moči, da se sooči z očetovimi sorodniki in ostalimi meščani. Dogodki, ki sledijo, začnejo Drewa spreminjati. Zacelijo se srčne rane in življenje spet dobi svoj smisel.
After causing a loss of almost one billion dollars in his company, the shoe designer Drew Baylor decides to commit suicide. However, in the exact moment of his act of despair, he receives a phone call from his sister telling him that his beloved father had just died in Elizabethtown, and he should bring him back since his mother had problem with the relatives of his father. He travels in an empty red eye flight and meets the attendant Claire Colburn, who changes his view and perspective of life.