Po uničenju poveljstva MI6 James Bond prestreže kodirano sporočilo, ki ga po poteh lastne preteklosti vodi v osrčje skrivne organizacije Spectre. Da bi razpletel mrežo spletk in prevar, mora najboljši agent njenega veličanstva zaščititi nedolžno hčerko večnega sovražnika. Med tem, ko se novi šef M ukvarja s političnimi silami, ki ogrožajo prihodnost MI6, se Bond na lastno pest poda na misijo od Mehike, preko Avstrije, do Maroka, v številnih obračunih in vrtoglavih pregonih pa se sooči tako s starimi, kot tudi novimi nevarnimi sovražniki.
A cryptic message from the past sends James Bond on a rogue mission to Mexico City and eventually Rome, where he meets Lucia, the beautiful and forbidden widow of an infamous criminal. Bond infiltrates a secret meeting and uncovers the existence of the sinister organisation known as SPECTRE. Meanwhile back in London, Max Denbigh, the new head of the Centre of National Security, questions Bond's actions and challenges the relevance of MI6 led by M. Bond covertly enlists Moneypenny and Q to help him seek out Madeleine Swann, the daughter of his old nemesis Mr White, who may hold the clue to untangling the web of SPECTRE. As the daughter of the assassin, she understands Bond in a way most others cannot. As Bond ventures towards the heart of SPECTRE, he learns a chilling connection between himself and the enemy he seeks.
