Indiana Jones v nočnem klubu spozna pevko Willie Scott. Willie z Indyjevo pomočjo komaj ubeži smrti, nato pa ju pot zanese v Indijo, kjer ju čaka velika avantura. Najti morata magični kamen, ki so ga ukradli prebivalcem neke vasice. Obeta se jima vrsta nepozabnih in napetih pustolovščin, borb za življenje in tudi romantičnih trenutkov, čeprav je sprva videti, da se Willie in Indy ne prenašata najbolje.
Set in 1935, a professor, archaeologist, and legendary hero by the name of Indiana Jones is back in action in his newest adventure. But this time he teams up with a night club singer named Wilhelmina "Willie" Scott and a twelve-year-old boy named Short Round. They end up in an Indian small distressed village, where the people believe that evil spirits have taken all their children away after a sacred precious stone was stolen! They also discovered the great mysterious terror surrounding a booby-trapped temple known as the Temple of Doom! Thuggee is beginning to attempt to rise once more, believing that with the power of all five Sankara stones they can rule the world! Now, it's all up to Indiana to put an end to the Thuggee campaign, rescue the lost children, win the girl and conquer the Temple of Doom.