V tretjem filmu o Indiani Jonesu bo Harrison Ford iskal čašo, iz katere naj bi Jezus Kristus pil med svojo zadnjo večerjo. Pitje iz te čaše menda zagotavlja večno mladost. Med iskanjem bo moral Indy obračunati z zlobnimi nacisti in iz njihovih krempljev rešiti očeta. Pot ga bo ponesla na različne konce sveta, spremljala pa ga bo lepa umetnostna zgodovinarka Elsa Schneider.
An art collector appeals to Jones to embark on a search for the Holy Grail. He learns that another archaeologist has disappeared while searching for the precious goblet, and the missing man is his own father, Dr. Henry Jones. The artifact is much harder to find than they expected, and its powers are too much for those impure in heart.