Kraljevi zdravnik v izgnanstvu kralja Karla II. se odloči pomagati Londončanom, ki trpijo zaradi kuge, medtem pa se zaljubi v prav tako revno dekle.
An aspiring young physician, Robert Merivel found himself in the service of King Charles II and saves the life of a spaniel dear to the King. Merivel joins the King's court and lives the high life provided to someone of his position. Merivel is ordered to marry one of the King's mistresses in order to divert the suspicions of another one of his mistresses. He is given one order by the king and that is not to fall in love. The situation worsens when Merivel finds himself in love with his new wife. Eventually, the King finds out and relieves Merivel of his position and wealth. His fall from grace leaves Merivel where he first started. And through his travels and reunites with an old friend, he rediscovers his love for true medicine and what it really means to be a physician.