V prihodnosti je razmnoževanje, kot ga poznamo danes, nesprejemljivo. Vsi otroci, spočeti na naraven način, so manjvredni, genetsko nepopolni in zaradi tega nezaželeni člani družbe. Vincent Freeman je bil spočet na staromoden način, iz ljubezni, zato skoraj nikjer ne dobi spodobnega dela. Sanja o službi pri vesoljski korporaciji Gattaca, vendar naloga ne bo lahka. Uspe mu šele, ko spozna genetsko izpopolnjenega Jeromea Morrowa, ki je zaradi nesreče prikovan na invalidski voziček. Vincent kupi njegovo identiteto in tako dobi delo pri Gattaci. Vendar se Vincentova prihodnost znajde na nitki.
In the not-too-distant future, a less-than-perfect man wants to travel to the stars. Society has categorized Vincent Freeman as less than suitable given his genetic make-up and he has become one of the underclass of humans that are only useful for menial jobs. To move ahead, he assumes the identity of Jerome Morrow, a perfect genetic specimen who is a paraplegic as a result of a car accident. With professional advice, Vincent learns to deceive DNA and urine sample testing. Just when he is finally scheduled for a space mission, his program director is killed and the police begin an investigation, jeopardizing his secret.