Zgodba se vrti okoli treh sester in njihovega hudo bolnega očeta. Najstarejša Georgia ustvarja priljubljeno revijo za ženske. Srednja Eve je žena in mama, ki mora ob vseh obveznostih skrbeti še za očeta. Najmlajša Maddie je obetavna igralka z vlogo v drugorazredni televizijski nadaljevanki. Njihova mama je že skoraj pozabljena, saj jih je pred mnogimi leti zapustila. Georgia, Eve in Maddie se le redko vidijo, zato pa kar naprej klepetajo po telefonu. Okoliščine nanesejo, da se zaradi očeta lepega dne srečajo v bolnišnici.
Georgia Mozell, Eve Marks and Maddy Mozell are adult sisters. Georgia is the editor of her own wildly successful self-titled women's magazine. She strives for publicity at any cost. Party planner Eve is the mother hen of the group, not only of her own family, but also of her siblings and father as their mother, Pat, not only emotionally left their father when they divorced, but her daughters as well. And Maddy is a vacuous soap opera actress who has always struggled for her own identity. Despite being as busy with her own life as the others, Eve is the only one of the three who deals with the long term hospitalization of their cantankerous seventy-nine year old father, Lou Mozell, when he enters the early stages of dementia, and the associated outcomes of that hospitalization. Eve's caring for Lou is despite an especially hurtful incident with him seven years earlier. As the emotional aspect of looking after Lou becomes more and more stressful, Eve has to figure out how to maintain her own sanity, while dealing with her sisters, who believe they too are part of their father's care while they don't lift a finger to help.