Zloglasni lovec na glave se odpravi v Transilvanijo, da bi obračunal z grofom Drakulo, ki se pri svojih novih zločinih poslužuje odkritij dr. Frainkensteina in volkodlakov.
Van Helsing is in the world to rid all evil, even if not everyone agrees with him. The Vatican sends the monster hunter and his ally, Carl, to Transylvania. They have been sent to this land to stop the powerful Count Dracula. Whilst there they join forces with a Gypsy Princess called Anna Valerious, who is determined to end an ancient curse on her family by destroying the vampire. They just don't know how!