Globoko v gozdovih Zahodne Virginije je opuščen sanatorij, ki so ga zaprli po tistem, ko se je izrojena družina ljudožerskih kmetavzarjev znesla nad tedanjim osebjem in prebivalci. Več let pozneje se je v odmaknjeno razpadajoče poslopje med snežnim neurjem prisiljena zateči skupina prijateljev s kolidža, ki v bližini preživlja zimske počitnice. Kmalu se srečajo z nekdanjimi bolniki v tisti ustanovi in edina možnost je ta, da se izrojenim morilcem uprejo.
Follows a group of friends that decide to go snowmobiling during their winter break. They make a "wrong turn", getting lost in a storm, and seek shelter in an abandoned sanatorium. They are completely isolated by the storm and are thankful they can get out of the elements. But the sanatorium has a troubled past, and some of its former patients still reside there and are not happy about the intrusion. In a deadly game of cat and mouse, the college kids must fight to survive the night.